British Society for Matrix Biology

Manchester 2005

25th Anniversary Meeting
Pathobiology of Bone and Cartilage

12-13th September 2005

Dr. Mike Briggs and Dr. Ray Boot-Handford.

A special meeting to mark the retirement of Professor Mike Grant

Monday 12^th September

Registration in foyer of Hulme Hall from 11.00 am.

 

12.00 - 1.00 pm        Lunch/Trade stands

1.00 pm                      Welcome

Session 1: Differentiation, pattern formation and morphogenesis in skeletal development

1.15 pm                      Stefan Mundlos (Max-Planck-Institute for Molecular Genetics, Berlin)

Function and Mutations of GDF5 in digit development

1.45 pm                      Frank Luyten (University of Leuven)

BMP signaling: from joint development to joint disease

2.15 pm                      Pip Francis-West (King's College, London)

Wnt/Wisp regulation of skeletal differentiation

2.45 pm                      Checco Ramirez (Hospital for Special Surgery, New York)

Role of architectural microfibrils in bone physiology 

3.15 pm                      Short talk selected from the abstracts

3.30 4.00 pm         Tea/trade stands

 

Session 2: Structure and function of the cartilage extracellular matrix

4.00 pm                      Kathy Cheah (University of Hong Kong)

Chondrocytes alleviate ER stress caused by unfolded proteins by reprogramming 

4.30 pm                      Dick Heinegard (University of Lund, Sweden)

                                    Diverse functions of matrix proteins in cartilage homeostasis

5.00 pm                      John Bateman (Royal Children's Hospital, Melbourne)

                                    TBA

5.30pm                       Short talk selected from the abstracts

 

6.00pm 7.30 pm   Posters and Wine Reception

7.30 pm                     Dinner

 

Tuesday 13^th September

Session 3: Genetic diseases of bone and cartilage

9.00 am                      Gillian Wallis (University of Manchester)

                                    Identification of susceptibility genes for rare and common forms of

Osteoarthritis

9.30 am                      Matt Warman (Case Western Reserve University, Cleveland)

                                    TBA 

10.00 am                    Michael Briggs (University of Manchester)

Pathomolecular mechanisms of chondrodysplasia in mice harbouring missense mutations in COMP and matrilin-3

10.30 am                    Short talk selected from the abstracts

10.45 - 11.15 am      Coffee/trade stands

 

Session 4: BSMB Society Session

11.15 am 1.00pm  Six short talks selected from the abstracts

 

1 pm 2 pm             Lunch/Trade stands

 

Session 5: Repair and regeneration of bone and cartilage

2.00 pm                      Peter Byers (University of Washington, Seattle)

Outcome of splice site mutations in collagen genes: the role of the

order of intron removal

2.30 pm                      Bruce Caterson (University of Cardiff, Wales)

Studies of cartilage metabolism using ex vivo cultured cartilage graft

3.00 pm                      Frank Barry (NUI Galway, Ireland)

                                    Stem cell-mediated repair of bone and cartilage

3.30 pm                      Tim Hardingham (University of Manchester)

                                    Chondrogenesis and the production of cartilage matrix

4.00 pm                      Short talk selected from the abstracts

4.15 pm                     Closing remarks and poster prize presentation