Norwich 2001

'THE IMPACT OF PROTEINASES ON MATRIX BIOLOGY'



University of East Anglia, Norwich
3-4 September 2001

Monday 2nd April

11.00 - onwards: Registration in LCR, Student's Union Bldg

13.00 - Introduction Lecture Theatre 3 - Ian Clark

Session 1:

13.15 - 14.00: Voon Wee Yong, U. Calgary, Canada: MMPs in the CNS - friend or foe?

14.00 - 14.45: Drew Rowan, U. Newcastle, UK: The effects of IL-17 on cartilage and chondrocytes.

14.45 - 15.30: John Iredale, U. Southampton, UK: Recovery from liver fibrosis: matrix degradation and the fate of the hepatic stellate cell.

15.30 - 16.10: Coffee and Poster viewing

Session 2:

1610 - 1650: Shu Ye, U. Southampton, UK: Polymorphisms in MMP and TIMP genes.

1650 - 1730: Vince Ellis, UEA, Norwich, UK: Mechanisms regulating plasmin generation in the pericellular environment

1830 - 2000: Wine reception and SCVA gallery viewing

2000 - : Conference dinner, Sainsbury Centre


Tuesday 4th September

Session 3:

09.15-09.55: Micky Tortorella, Kennedy Institute, UK: The role and regulation of ADAM-TS4 (Aggrecanase-1) and ADAM-TS5 (Aggrecanase-2) in cartilage catabolism.

09.55 - 10.15: Deepa Nath, UEA, Norwich, UK: Regulation of ectodomain shedding through activation of different cell surface receptors.

10.15 - 10.35: Zara Poghosyan, UEA, Norwich, UK: Adamalysins and tyrosine kinases: a tale of tails.

10.35 - 11.15: Coffee and Poster viewing

11.15- 12.15: 4 x poster talks

12.15 - 13.45: Lunch LCR

Session 4:

13.45 - 14.30: Andy Baker, U. Glasgow, UK: Death by TIMP-3: Insights into mechanisms and exploitation in gene therapy for disease.

14.30 - 1515: Kevin Leco, U. Western Ontario, Canada: Development of the mouse lung in the absence of TIMP-3.